A Case of IgG4-Related Disease Presenting as Massive Pleural Effusion and Thrombophlebitis

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ÃÖÁ¾Çö(Choi Jong-Hyun) - Korea University College of Medicine Department of Internal Medicine
½ÉÀç°â(Sim Jae-Kyeom) - Korea University College of Medicine Department of Internal Medicine
¿ÀÁö¿¬(Oh Jee-Youn) - Korea University College of Medicine Department of Internal Medicine
ÀÌÀºÁÖ(Lee Eun-Joo) - Korea University College of Medicine Department of Internal Medicine
Çã±Ô¿µ(Hur Gyu-Young) - Korea University College of Medicine Department of Internal Medicine
À̽ÂÇå(Lee Seung-Heon) - Korea University College of Medicine Department of Internal Medicine
À̼º¿ë(Lee Sung-Yong) - Korea University College of Medicine Department of Internal Medicine
±èÁ¦Çü(Kim Je-Hyeong) - Korea University College of Medicine Department of Internal Medicine
ÀÌ»ó¿±(Lee Sang-Yeub) - Korea University College of Medicine Department of Internal Medicine
½Åö(Shin Chol) - Korea University College of Medicine Department of Internal Medicine
½ÉÀçÁ¤(Shim Jae-Jeong) - Korea University College of Medicine Department of Internal Medicine
Àα¤È£(In Kwang-Ho) - Korea University College of Medicine Department of Internal Medicine
°­°æÈ£(Kang Kyung-Ho) - Korea University College of Medicine Department of Internal Medicine
¹Î°æÈÆ(Min Kyung-Hoon) - Korea University College of Medicine Department of Internal Medicine

Abstract

Immunoglobulin (Ig) G4-related disease is a recently recognized systemic fibroinflammatory condition characterized by a lymphoplasmacytic infiltrate rich in IgG4-positive plasma cells with elevated circulating levels of IgG4. The disease can either be localized to one or two organs, or present as diffuse multi-organ disease. Furthermore, lesions in different organs can present simultaneously or metachronously. In the pulmonary manefestations, lesions associated with IgG4-related disease have been described in the lung parenchyma, airways and pleura, as well as the mediastinum. We report a case of IgG4-related disease presenting as massive pleural effusion and thrombophlebitis.

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Immunoglobulin G, Pleural Effusion, Thrombophlebitis
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